{"id":16324,"date":"2025-12-10T08:29:45","date_gmt":"2025-12-10T08:29:45","guid":{"rendered":"https:\/\/www.epicmicron.com\/?post_type=astra-portfolio&p=16324"},"modified":"2025-12-10T08:30:54","modified_gmt":"2025-12-10T08:30:54","slug":"progesterone-powder-production-line-with-disc-jet-mill","status":"publish","type":"astra-portfolio","link":"https:\/\/www.epicmicron.com\/nl\/cases\/progesterone-powder-production-line-with-disc-jet-mill\/","title":{"rendered":"Productielijn voor progesteronpoeder met schijfstraalmolen"},"content":{"rendered":"

A mid-sized pharmaceutical CDMO specializing in hormone-based APIs was looking for a jet mill in producing ultra-fine progesterone powder. It should meet strict particle size requirements for better bioavailability and formulation performance. Their existing milling equipment struggled with heat-sensitive materials like progesterone. It often results in inconsistent particle distribution, product degradation, and low throughput.<\/p>\n\n\n\n

\"progesteronpoeder\"<\/figure>\n\n\n\n

De klant kwam voor het eerst in aanraking met... Episch poeder<\/a> Via een betrouwbare contactpersoon in de branche. Het betreft een bedrijf in een aanverwante sector dat al enkele jaren met succes onze luchtclassificatiemolens gebruikte. Onder de indruk van de resultaten en de positieve feedback van die referentie, namen ze contact met ons op om te onderzoeken of onze straalmolentechnologie hun behoeften op het gebied van progesteronpoedermicronisatie kon vervullen.<\/p>\n\n\n\n

After initial discussions and material testing at our facility, we recommended the MQP06 disc jet mill. The system\u2019s fluid energy design, precise control, and fully enclosed, GMP-compliant construction were a perfect match for their heat-sensitive, high-value API.<\/p>\n\n\n\n

Tijdens proeven op locatie met hun eigen progesterongrondstof kon de klant het proces in realtime volgen: geen meetbare temperatuurstijging, vrijwel geen productverlies en een schone, smalle deeltjesgrootteverdeling die hun eerdere resultaten ruimschoots overtrof. Ook de operationele eenvoud en het gemakkelijke reinigen vielen op \u2013 dankzij de volledige CIP-functionaliteit konden ze snel tussen batches wisselen zonder risico op kruisbesmetting.<\/p>\n\n\n\n

Na de installatie integreerde de MQP06 naadloos in hun bestaande productielijn. De operators waardeerden de intu\u00eftieve HMI en het feit dat het systeem minimale parameteraanpassingen vereiste om dag in dag uit aan de specificaties te voldoen. Het onderhoud was eenvoudig en ons supportteam op afstand reageerde snel wanneer er fijnafstelling nodig was.<\/p>\n\n\n\n

De klant voert nu met vertrouwen campagnes voor de micronisatie van progesteron uit. Het bereiken van een consistente kwaliteit heeft hun positie bij partners in de vervolgfase van de formulering versterkt.<\/p>\n\n\n\n

\"MQP10<\/figure>\n\n\n\n

Belangrijkste behaalde parameters<\/h2>\n\n\n\n

Materiaal:<\/strong> Progesteron<\/p>\n\n\n\n

Deeltjesgrootte:<\/strong> d99 < 14 \u03bcm<\/p>\n\n\n\n

Uitgang:<\/strong> 20 kg\/u<\/p>\n\n\n\n

Apparatuur: <\/strong>Epic Powder MQP06 Disc Jet Mill<\/p>","protected":false},"featured_media":16314,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"astra-portfolio-categories":[46],"astra-portfolio-other-categories":[],"astra-portfolio-tags":[],"class_list":["post-16324","astra-portfolio","type-astra-portfolio","status-publish","has-post-thumbnail","hentry","astra-portfolio-categories-pharmaceutical"],"astra-site-call-to-action":"","astra-site-open-in-new-tab":0,"astra-site-open-portfolio-in":"new-tab","astra-site-url":"","thumbnail-image-url":null,"thumbnail-image-meta":{"alt":"","title":""},"lightbox-image-url":null,"portfolio-type":"page","portfolio-video-url":"","request_time":0.12367391586303711,"yoast_head":"\nProgesterone Powder Production Line with Disc Jet Mill - 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