{"id":16324,"date":"2025-12-10T08:29:45","date_gmt":"2025-12-10T08:29:45","guid":{"rendered":"https:\/\/www.epicmicron.com\/?post_type=astra-portfolio&#038;p=16324"},"modified":"2025-12-10T08:30:54","modified_gmt":"2025-12-10T08:30:54","slug":"progesterone-powder-production-line-with-disc-jet-mill","status":"publish","type":"astra-portfolio","link":"https:\/\/www.epicmicron.com\/fr\/cases\/progesterone-powder-production-line-with-disc-jet-mill\/","title":{"rendered":"Ligne de production de poudre de progest\u00e9rone avec broyeur \u00e0 disque"},"content":{"rendered":"<p>A mid-sized pharmaceutical CDMO specializing in hormone-based APIs was looking for a jet mill in producing ultra-fine progesterone powder. It should meet strict particle size requirements for better bioavailability and formulation performance. Their existing milling equipment struggled with heat-sensitive materials like progesterone. It often results in inconsistent particle distribution, product degradation, and low throughput.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"640\" height=\"426\" src=\"https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/progesterone-powder.webp\" alt=\"poudre de progest\u00e9rone\" class=\"wp-image-16325\" style=\"width:720px;height:auto\" srcset=\"https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/progesterone-powder.webp 640w, https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/progesterone-powder-300x200.webp 300w, https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/progesterone-powder-18x12.webp 18w, https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/progesterone-powder-600x399.webp 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure>\n\n\n\n<p>Le client a d&#039;abord appris que <a href=\"https:\/\/www.epicmicron.com\/fr\/products\/\">Poudre \u00e9pique<\/a> Par l&#039;interm\u00e9diaire d&#039;un contact de confiance du secteur, une entreprise d&#039;un secteur connexe qui utilisait avec succ\u00e8s nos broyeurs \u00e0 classification pneumatique depuis plusieurs ann\u00e9es, a \u00e9t\u00e9 impressionn\u00e9e par les r\u00e9sultats et les retours positifs de cette r\u00e9f\u00e9rence. Elle nous a alors contact\u00e9s pour savoir si notre technologie de broyage \u00e0 jet pouvait r\u00e9pondre \u00e0 ses besoins en mati\u00e8re de micronisation de la progest\u00e9rone en poudre.<\/p>\n\n\n\n<p>After initial discussions and material testing at our facility, we recommended the MQP06 disc jet mill. The system\u2019s fluid energy design, precise control, and fully enclosed, GMP-compliant construction were a perfect match for their heat-sensitive, high-value API.<\/p>\n\n\n\n<p>Lors d&#039;essais sur site avec leur propre mati\u00e8re premi\u00e8re de progest\u00e9rone, le client a pu observer le proc\u00e9d\u00e9 en temps r\u00e9el\u00a0: aucune hausse de temp\u00e9rature mesurable, des pertes de produit quasi nulles et une granulom\u00e9trie fine et homog\u00e8ne, surpassant largement leurs r\u00e9sultats pr\u00e9c\u00e9dents. La simplicit\u00e9 d&#039;utilisation et la facilit\u00e9 de nettoyage ont \u00e9galement \u00e9t\u00e9 des atouts majeurs\u00a0: la capacit\u00e9 de nettoyage en place (NEP) compl\u00e8te leur a permis de passer rapidement d&#039;un lot \u00e0 l&#039;autre sans risque de contamination crois\u00e9e.<\/p>\n\n\n\n<p>Une fois install\u00e9e, la MQP06 s&#039;est parfaitement int\u00e9gr\u00e9e \u00e0 leur ligne de production existante. Les op\u00e9rateurs ont appr\u00e9ci\u00e9 l&#039;interface homme-machine intuitive et le fait que le syst\u00e8me ne n\u00e9cessitait que des r\u00e9glages minimes pour atteindre les sp\u00e9cifications cibles jour apr\u00e8s jour. La maintenance s&#039;est av\u00e9r\u00e9e simple et notre \u00e9quipe d&#039;assistance \u00e0 distance a toujours \u00e9t\u00e9 r\u00e9active pour les ajustements n\u00e9cessaires.<\/p>\n\n\n\n<p>Le client m\u00e8ne d\u00e9sormais ses campagnes de micronisation de la progest\u00e9rone en toute confiance. L&#039;obtention d&#039;une qualit\u00e9 constante a renforc\u00e9 sa position aupr\u00e8s de ses partenaires de formulation en aval.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img decoding=\"async\" width=\"1000\" height=\"750\" src=\"https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/MQP10-Flat-Disc-Jet-Mill-1.webp\" alt=\"Broyeur \u00e0 jet d&#039;air \u00e0 disque plat MQP10\" class=\"wp-image-16315\" style=\"width:684px;height:auto\" srcset=\"https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/MQP10-Flat-Disc-Jet-Mill-1.webp 1000w, https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/MQP10-Flat-Disc-Jet-Mill-1-300x225.webp 300w, https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/MQP10-Flat-Disc-Jet-Mill-1-768x576.webp 768w, https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/MQP10-Flat-Disc-Jet-Mill-1-16x12.webp 16w, https:\/\/www.epicmicron.com\/wp-content\/uploads\/2025\/12\/MQP10-Flat-Disc-Jet-Mill-1-600x450.webp 600w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\">Principaux param\u00e8tres atteints<\/h2>\n\n\n\n<p><strong>Mat\u00e9riel:<\/strong> Progest\u00e9rone<\/p>\n\n\n\n<p><strong>Taille des particules :<\/strong> d99 &lt; 14 \u03bcm<\/p>\n\n\n\n<p><strong>Sortir:<\/strong> 20 kg\/h<\/p>\n\n\n\n<p><strong>\u00c9quipement: <\/strong>Epic Powder MQP06 Disc Jet Mill<\/p>","protected":false},"featured_media":16314,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"astra-portfolio-categories":[46],"astra-portfolio-other-categories":[],"astra-portfolio-tags":[],"class_list":["post-16324","astra-portfolio","type-astra-portfolio","status-publish","has-post-thumbnail","hentry","astra-portfolio-categories-pharmaceutical"],"astra-site-call-to-action":"","astra-site-open-in-new-tab":0,"astra-site-open-portfolio-in":"new-tab","astra-site-url":"","thumbnail-image-url":null,"thumbnail-image-meta":{"alt":"","title":""},"lightbox-image-url":null,"portfolio-type":"page","portfolio-video-url":"","request_time":0.12895703315734863,"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - 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