{"id":16324,"date":"2025-12-10T08:29:45","date_gmt":"2025-12-10T08:29:45","guid":{"rendered":"https:\/\/www.epicmicron.com\/?post_type=astra-portfolio&p=16324"},"modified":"2025-12-10T08:30:54","modified_gmt":"2025-12-10T08:30:54","slug":"progesterone-powder-production-line-with-disc-jet-mill","status":"publish","type":"astra-portfolio","link":"https:\/\/www.epicmicron.com\/de\/cases\/progesterone-powder-production-line-with-disc-jet-mill\/","title":{"rendered":"Produktionslinie f\u00fcr Progesteronpulver mit Scheibenstrahlm\u00fchle"},"content":{"rendered":"

A mid-sized pharmaceutical CDMO specializing in hormone-based APIs was looking for a jet mill in producing ultra-fine progesterone powder. It should meet strict particle size requirements for better bioavailability and formulation performance. Their existing milling equipment struggled with heat-sensitive materials like progesterone. It often results in inconsistent particle distribution, product degradation, and low throughput.<\/p>\n\n\n\n

\"Progesteronpulver\"<\/figure>\n\n\n\n

Der Kunde erfuhr zuerst von Episches Pulver<\/a> \u00dcber einen vertrauensw\u00fcrdigen Branchenkontakt. Es handelt sich um ein Unternehmen aus einem angrenzenden Sektor, das unsere Windsichterm\u00fchlen bereits seit mehreren Jahren erfolgreich einsetzt. Beeindruckt von den Ergebnissen und dem positiven Feedback dieses Referenzunternehmens, wandten sie sich an uns, um zu erfahren, ob unsere Strahlm\u00fchlentechnologie ihre Anforderungen an die Mikronisierung von Progesteronpulver erf\u00fcllen k\u00f6nnte.<\/p>\n\n\n\n

After initial discussions and material testing at our facility, we recommended the MQP06 disc jet mill. The system\u2019s fluid energy design, precise control, and fully enclosed, GMP-compliant construction were a perfect match for their heat-sensitive, high-value API.<\/p>\n\n\n\n

Bei Vor-Ort-Tests mit ihrem eigenen Progesteron-Rohmaterial konnte der Kunde den Prozess in Echtzeit beobachten: kein messbarer Temperaturanstieg, praktisch kein Produktverlust und eine saubere, enge Partikelgr\u00f6\u00dfenverteilung, die ihre bisherigen Ergebnisse deutlich \u00fcbertraf. Besonders hervorzuheben sind die einfache Bedienung und die unkomplizierte Reinigung \u2013 dank der vollst\u00e4ndigen CIP-Reinigung konnten sie schnell und ohne Risiko einer Kreuzkontamination zwischen den Chargen wechseln.<\/p>\n\n\n\n

Nach der Installation lie\u00df sich das MQP06 reibungslos in die bestehende Produktionslinie integrieren. Die Bediener sch\u00e4tzten die intuitive Benutzeroberfl\u00e4che und die Tatsache, dass das System nur minimale Parameteranpassungen ben\u00f6tigte, um die Zielvorgaben Tag f\u00fcr Tag zu erreichen. Die Wartung gestaltete sich unkompliziert, und unser Remote-Support-Team reagierte stets prompt, wenn Feineinstellungen erforderlich waren.<\/p>\n\n\n\n

Der Kunde f\u00fchrt nun Progesteron-Mikronisierungskampagnen mit Zuversicht durch. Die Erzielung einer gleichbleibenden Qualit\u00e4t hat seine Position bei den nachgelagerten Formulierungspartnern gest\u00e4rkt.<\/p>\n\n\n\n

\"MQP10<\/figure>\n\n\n\n

Wichtigste erreichte Parameter<\/h2>\n\n\n\n

Material:<\/strong> Progesteron<\/p>\n\n\n\n

Partikelgr\u00f6\u00dfe:<\/strong> d99 < 14 \u03bcm<\/p>\n\n\n\n

Ausgang:<\/strong> 20 kg\/h<\/p>\n\n\n\n

Ausr\u00fcstung: <\/strong>Epic Powder MQP06 Disc Jet Mill<\/p>","protected":false},"featured_media":16314,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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